November Webinar

September Webinar

Is There a Proton-Specific Biological Response in UHDR?

05 November 2024 at 17:00 – 18:30 CET/GMT+1

 

Our Chairs:

Elham Santina
United Kingdom
Michael Taylor
United Kingdom

Postdoctoral Research Associate at The University of Manchester

Senior Lecturer in Proton Therapy Physics at The University of Manchester

Meet Our Speakers:

Anaig Bertho
Postdoctoral Researcher in Radiobiology
Institut Curie
France
Theresa Busch
Professor and Associate Director of the Division of Research
Department of Radiation Oncology
University of Pennsylvania
Mathieu Sertoio
Assistant Professor
Radiation Oncology Department
University of Cincinnati College of Medicine

Presentation Title: “pFLASH & eFLASH in the Brain: Is There a Proton-Specific Biological Response in UHDR?”

Presentation Title: “The Biology and Benefits of Protons in FLASH Radiotherapy”

Presentation Title: “How Might Proton vs. Electron FLASH Radiotherapy Shape Our Understanding of FLASH Effects?”

Annaïg Bertho is a postdoctoral researcher in radiobiology at the Institut Curie, France. She is part of the “New Approaches in Radiotherapy” team, led by Dr. Yolanda Prezado. Her research focuses on understanding the physiopathological and radiobiological mechanisms in response to innovative radiotherapy techniques, particularly mini-beam and FLASH radiation therapy.

She holds a PhD in Physiology, Pathophysiology, and Therapeutics from Sorbonne University. Since 2020, her research has explored, among other, the immune response to minibeam radiation therapy, the potential benefits of thoracic proton minibeam therapy, and the role of oxygen supplementation during anesthesia in proton FLASH and conventional proton therapy. She has authored 14 publications and received 3 awards for her contributions to the field.

Her goal is to develop radiotherapy approaches that improve tumor control while minimizing side effects, ultimately enhancing the quality of life for cancer patients.

Theresa M. Busch, PhD is professor and Associate Director of the Division of Research, Department of Radiation Oncology at the University of Pennsylvania. Dr. Busch’s laboratory performs translational research in the study of tumor microenvironment as it relates to radiation therapy, delivered as nonionizing radiation in the form of photodynamic therapy or ionizing radiation generated by photons or protons. This includes research of high dose rate FLASH proton radiotherapy in sparing of normal tissues. Using mechanistic knowledge gained from these studies, her laboratory investigates clinically relevant approaches to improve the therapeutic window of cancer treatment.

Dr. Busch is involved in national and international societies on photomedical and radiation oncology research. She is currently Treasurer for the American Society for Photobiology. She serves as Vice Chair for Community Engagement and Inclusivity in the Department of Radiation Oncology and is Co-director of the Radiobiology and Imaging Program at the University of Pennsylvania Abramson Cancer Center.

Dr. Sertorio is an Assistant Professor in the Radiation Oncology department at the University of Cincinnati College of Medicine. Dr. Sertorio research focuses on development of new cancer therapy approaches based on photon and proton therapy and tumor specific genetic/biologic features to improve cancer treatment outcome and radiation exposure toxicity. His research aims to develop new drugs and immunomodulatory strategies in combination with radiotherapy. Dr. Sertorio is conducting research projects on proton FLASH radiotherapy to generate pre-clinical data in support of new FLASH radiotherapy clinical trials.

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